Mouse anti-Human HEPH polyclonal antibody

Species Reactivity

Human

Immunogen

HEPH (NP_620074, 315 a.a. ~ 424 a.a) partial recombinant protein with GST tag. The sequence is TRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDL LTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRI

Conjugate

Alternative Names

HEPH; hephaestin; CPL;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the multicopper oxidase protein family. The encoded protein is involved in the transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system, and may be involved in copper transport and homeostasis. In mouse, defects in this gene can lead to severe microcytic anemia. Alternative splicing results in multiple transcript variants.

Pathway

Iron uptake and transport; Mineral absorption; Transmembrane transport of small molecules;