Anti-HDAC6 monoclonal antibody (DCABH-2741) Knockout Validated

Rabbit anti-Human HDAC6 monoclonal antibody for WB, IHC-P, ICC/IF, IP

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS2709(3
Species Reactivity
Human, Monkey
Immunogen
Synthetic peptide corresponding to residues near the N-terminus in Human HDAC6 (UniProt ID: Q9UBN7).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/10000 - 1/50000; IHC-P: 1/50 - 1/100; ICC/IF: 1/500 - 1/1000; IP: 1/10 - 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HDAC6; histone deacetylase 6; FLJ16239; HD6; JM21; KIAA0901
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cell cycle, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class II, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Cayado-Gutierrez, N; Moncalero, VL; et al. Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN. CELL STRESS & CHAPERONES 18:243-249(2013).
Raju, I; Abraham, EC; et al. Congenital Cataract Causing Mutants of alpha A-Crystallin/sHSP Form Aggregates and Aggresomes Degraded through Ubiquitin-Proteasome Pathway. PLOS ONE 6:-(2011).

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