Specifications
Immunogen
Synthetic peptide corresponding to residues in Human HDAC11 (UniProt Q96DB2).
Applications
Application Notes
WB: 1/1000 - 1/10000; IP: 1/10 - 1/100;
Target
Alternative Names
HDAC11; histone deacetylase 11; HD11; FLJ22237;
Product Background
Antigen Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Pathway
NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class II, organism-specific biosystem;
Citations
Publication ()
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COA
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