Anti-HDAC11 monoclonal antibody

Antibody Isotype

IgG

Clone

FQS22453(C)

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to residues in Human HDAC11 (UniProt Q96DB2).

Conjugate

Unconjugated

Application Notes

WB: 1/1000 - 1/10000; IP: 1/10 - 1/100;

Alternative Names

HDAC11; histone deacetylase 11; HD11; FLJ22237;

Entrez Gene ID

79885

UniProt ID

Q96DB2

Antigen Description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Pathway

NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class II, organism-specific biosystem;

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More