A synthetic peptide from the 1t cytoplasmic domain of human HCN2 + HCN4, conjugated to an immunogenic carrier protein. The antigen is homologous in rat and mouse.
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/300 - 1/4000. Antigen retrieval is recommended before commencing with IHC staining protocol. IHC-Fr: 1/300 - 1/4000. WB: 1/300 - 1/4000. Predicted molecular weights: 97 and 129 kDa.
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Mistrik, P; Mader, R; et al. The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides. JOURNAL OF BIOLOGICAL CHEMISTRY 280:27056-27061(2005).
Pian, P; Bucchi, A; et al. Regulation of Gating and rundown of HCN hyperpolarization-activated channels by exogenous and endogenous PIP2. JOURNAL OF GENERAL PHYSIOLOGY 128:593-604(2006).
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COA
Certificate of Analysis
