General Notes
This product (Catalog No. DPABH-01453) is a rabbit-derived polyclonal antibody raised against human HAS3, targeting the amino acid region 1–281 of the protein. This antibody exhibits cross-reactivity with Human HAS3 from mouse and rat. It has been affinity purified by Protein A. HAS3(hyaluronan synthase 3) belongs to the NodC/HAS family, which are widely expressed in human tissues and appear to function in embryogenesis, wound healing and other processes associated with cellular proliferation and migration(PMID:14566823). HAS3 is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. It may play a role in the progression of colon cancer and, as such, may provide novel targets for diagnostic and therapeutic interventions(PMID:14566823). It has 2 isoforms produced by alternative splicing and the protein has a glycosylation site.
DPABH-01453 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:100–1:400) applications.
DPABH-01453 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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