Anti-HAS3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human HAS3 is used for rabbit immunization.

Conjugate

Alternative Names

HAS3; hyaluronan synthase 3; HA synthase 3; hyaluronate synthase 3; hyaluronic acid synthase 3;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.

Pathway

Disease; Glycosaminoglycan metabolism; Hyaluronan biosynthesis and export; Hyaluronan metabolism; MPS I - Hurler syndrome; MPS II - Hunter syndrome; MPS IIIA - Sanfilippo syndrome A; MPS IIIB - Sanfilippo syndrome B; MPS IIIC - Sanfilippo syndrome C; MPS IIID - Sanfilippo syndrome D; MPS IV - Morquio syndrome A;