Anti-HARS2 monoclonal antibody, clone 7G0

Antibody Isotype

IgG2b

Clone

7G0

Species Reactivity

Human

Immunogen

Recombinant full length Human HARS2 (NP_036340) produced in HEK293T cell.

Conjugate

Application Notes

WB: 1/2000; IHC-P: 1/150; Flow Cyt: 1/100;

Alternative Names

HARS2; histidyl-tRNA synthetase 2, mitochondrial (putative); HARSL, histidyl tRNA synthetase like; probable histidine--tRNA ligase, mitochondrial; HARSR; histidine tRNA ligase 2; mitochondrial (putative); HO3; hisRS; HARS-related; histidine translase; hi

Entrez Gene ID

UniProt ID

Antigen Description

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes share a bidirectional promoter.

Pathway

Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Gene Expression, organism-specific biosystem; Mitochondrial tRNA aminoacylation, organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem.