Anti-HADHA monoclonal antibody (DCABH-285)

Mouse anti-Human HADHA monoclonal antibody for ICC, IHC-P, FC, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
5B9CH23
Species Reactivity
Rat, Cow, Human
Immunogen
Human heart mitochondria
Conjugate
Unconjugated

Applications


Application Notes
ICC: 5 μg/ml; Flow Cyt: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; hydroxyacyl Coenzyme A dehydrogenase/3 ketoacyl Coenzyme A thiolase/enoyl Coenzyme A hydratase (trifunctional protein), alpha subunit
Entrez Gene ID
UniProt ID

Product Background


Pathway
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA, organism-specific biosystem; Beta oxidation of hexanoyl-CoA to butanoyl-CoA, organism-specific biosystem; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA, organism-specific biosystem; Beta oxidation of myristoyl-CoA to lauroyl-CoA, organism-specific biosystem; Beta oxidation of octanoyl-CoA to hexanoyl-CoA, organism-specific biosystem; Beta oxidation of palmitoyl-CoA to myristoyl-CoA, organism-specific biosystem; Biosynthesis of unsaturated fatty acids, organism-specific biosystem;

Citations


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References


Zhu, Y; Soto, J; et al. Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1 alpha. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 305:H41-H51(2013).
Louden, ED; Luzzo, KM; et al. TallyHO obese female mice experience poor reproductive outcomes and abnormal blastocyst metabolism that is reversed by metformin. REPRODUCTION FERTILITY AND DEVELOPMENT 27:31-39(2015).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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