Rabbit Anti-Human GUCY2F (a.a. 71-398) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human GUCY2F protein; Source: E. coli derived, PET28a; Tag: 6*His; Domain: 71-398 aa of BC156674

Conjugate

Application Notes

WB: 1:500-1:1000
IHC: 1:20-1:200

General Notes

This product (Catalog No. DPABH-28271) is a rabbit-derived polyclonal antibody raised against human GUCY2F, targeting the amino acid region 71–398 of the protein. This antibody exhibits cross-reactivity with Human GUCY2F from mouse. It has been affinity purified by Protein A. GUCY2F(Guanylate cyclase 2F, retinal) is also named as GUC2F, RETGC2 and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. GUCY2F may play a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. By in situ hybridization, mRNA encoding GUCY2F is found only in the outer nuclear layer and inner segments of photoreceptor cells. By using synthetic peptide antiserum specific for each RetGC subtype, RetGC-2(GUCY2F) can be distinguished from RetGC-1 as a slightly smaller protein in immunoblots of bovine rod outer segments.(PMID:7777544).
DPABH-28271 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:20–1:200) applications.
DPABH-28271 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

CYGF; GC F; guanylate cyclase 2F; retinal; Guanylate cyclase F; GUC2DL; GUC2F; GUCY2F; RETGC 2; RETGC2; Retinal guanylyl cyclase 2; ROS GC2

Entrez Gene ID

UniProt ID