Anti-GUCY2F monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human GUCY2F is used for rabbit immunization.

Conjugate

Alternative Names

GUCY2F; guanylate cyclase 2F, retinal; retinal guanylyl cyclase 2; CYGF; GC F; guanylate cyclase 2D like; membrane (retina specific); GUC2DL; RetGC 2; ROS GC2; guanylate cyclase F; rod outer segment membrane guanylate cyclase 2; guanylate cyclase 2D-like,

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.

Pathway

Phototransduction, organism-specific biosystem; Phototransduction, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Visual signal transduction: Cones, organism-specific biosystem; Visual signal transduction: Rods, organism-specific biosystem;