Anti-GSPT2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human GSPT2 is used for rabbit immunization.

Conjugate

Alternative Names

GSPT2; G1 to S phase transition 2; eukaryotic peptide chain release factor GTP-binding subunit ERF3B; eRF3b; FLJ10441; eukaryotic peptide chain release factor subunit 3b; GST2; ERF3B;

Entrez Gene ID

UniProt ID

Antigen Description

GSPT2 is closely related to GSPT1 (MIM 139259), a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1 (MIM 600285), functions as a polypeptide chain release factor.

Pathway

Eukaryotic Translation Termination, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense Mediated Decay Independent of the Exon Junction Complex, organism-specific biosystem; Nonsense-Mediated Decay, organism-specific biosystem; Translation, organism-specific biosystem;