Anti-GGA3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human GGA3 is used for rabbit immunization.

Conjugate

Alternative Names

GGA3; golgi-associated, gamma adaptin ear containing, ARF binding protein 3; ADP-ribosylation factor-binding protein GGA3; KIAA0154; Golgi-localized, gamma ear-containing, ARF-binding protein 3; golgi associated, gamma adaptin ear containing, ARF binding

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Alternative splicing of this gene results in two transcript variants.

Pathway

Arf1 pathway, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;