Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GGA3 aa 400-600. The exact sequence is proprietary.Database link: Q9NZ52
Applications
Application Notes
IHC-P: 1/50; WB: 1/1000 - 1/10000; Flow Cyt: 1/20.
Target
Alternative Names
GGA3; golgi-associated, gamma adaptin ear containing, ARF binding protein 3; ADP-ribosylation factor-binding protein GGA3; KIAA0154; Golgi-localized, gamma ear-containing, ARF-binding protein 3; golgi associated, gamma adaptin ear containing, ARF binding
Product Background
Antigen Description
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
Pathway
Arf1 pathway, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem.
Citations
Publication ()
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COA
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