Rabbit Anti-Human GFM2 (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from internal of human GFM2.

Conjugate

Application Notes

WB: 1:500-1:3000
IF: 1:100-1:500

General Notes

This product (Catalog No. DPABH-23318) is a rabbit-derived IgG polyclonal antibody raised against human GFM2. This antibody exhibits cross-reactivity with GFM2 from mouse. It has been affinity purified by protein A. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
DPABH-23318 is suitable for use in Western blot (WB) (1:500–1:3,000), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-23318 is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

EF-G 2; EFG2; elongation factor G 2; mitochondrial; elongation factor G2

Entrez Gene ID

UniProt ID