Anti-GBP2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human GBP2 is used for rabbit immunization.

Conjugate

Alternative Names

GBP2; guanylate binding protein 2, interferon-inducible; interferon-induced guanylate-binding protein 2; GBP-2; huGBP-2; GTP-binding protein 2; guanine nucleotide-binding protein 2; DKFZp451C2311;

Entrez Gene ID

UniProt ID

Antigen Description

Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.

Pathway

Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon alpha/beta signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem;