Mouse anti-Human GATA6 polyclonal antibody

Species Reactivity

Human

Immunogen

GATA6 (NP_005248, 496 a.a. ~ 595 a.a) partial recombinant protein with GST tag. The sequence is KNINKSKTCSGNSNNSIPMTPTSTSSNSDDCSKNTSPTTQPTASGAGAPVMTGAGESTNP ENSELKYSGQDGLYIGVSLASPAEVTSSVRPDSWCALALA

Conjugate

Alternative Names

GATA6; GATA binding protein 6; transcription factor GATA-6; GATA-binding factor 6;

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects.

Pathway

Factors involved in megakaryocyte development and platelet production; Hemostasis;