Mouse myeloma cell line NS0-derived recombinant mouse Gas1. Leu39-Ser315 Accession Number Q01721
Conjugate
Biotin
Applications
Application Notes
Western Blot 0.1 μg/mL; ELISA Capture 0.2-0.8 μg/mL; ELISA Detection 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DPABY-327 - DPABY-649
Target
Alternative Names
GAS1; growth arrest specific 1; Gas-1; AW554192; growth arrest-specific protein 1;
The growth arrest-specific genes are related by their induction following cellular stress. Gas1 is a GPI-linked membrane glycoprotein that blocks entry to S phase cell cycle. Gas1 inhibits cell proliferation, protects endothelial cells from apoptosis, and promotes excitotoxic neuronal death. Gas6 is a vitamin K-dependent protein with a gamma-carboxylated amino terminus (Gla domain), four EGF-like repeats, and C-terminal globulin-like domains. Gas6 is a ligand for the Axl, Dtk, and Mer tyrosine kinase receptors. Gas6 is mitogenic and anti-apoptotic for some cell types and also promotes cell adhesion.
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