Anti-GAD1 polyclonal antibody (DPABH-20152)

Goat anti-Human GAD1 (aa 526-537) polyclonal antibody for WB, IHC-P Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide: C-PDSPQRREKLHK, corresponding to internal sequence amino acids 526-537 of Human GAD1 (NP_000808.2).
Conjugate
Unconjugated

Applications


Application Notes
WB: 0.3 - 1μg/ml; IHC-P: 4μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
GAD1; glutamate decarboxylase 1 (brain, 67kDa); GAD; SCP; CPSQ1; glutamate decarboxylase 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alanine and aspartate metabolism; Alanine, aspartate and glutamate metabolism; Butanoate metabolism; GABA (gamma-Aminobutyrate) shunt

Citations


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References


Lynex, CN; Carr, IM; et al. Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders. BMC NEUROLOGY 4:-(2004).
Rambrand, T; Pociot, F; et al. Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings. HUMAN GENETICS 99:177-185(1997).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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