Anti-FXR2 monoclonal antibody (DCABH-11635) Made to order

Rabbit anti-Human FXR2 monoclonal antibody for WB, ELISA

View other FXR2 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human FXR2 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
FXR2; fragile X mental retardation, autosomal homolog 2; FMR1L2; fragile X mental retardation syndrome-related protein 2; fragile X-mental retardation 1-like 2; FXR2P
Entrez Gene ID
UniProt ID

Product Background


Gene summary
FXR2 (FMR1 Autosomal Homolog 2) is a Protein Coding gene. Diseases associated with FXR2 include fragile x syndrome and x-linked disease. Among its related pathways are RNA transport. GO annotations related to this gene include nucleic acid binding and identical protein binding. An important paralog of this gene is FXR1. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.
Antigen Description
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. RNA-binding protein. Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene. The protein encoded by this gene is an RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. The function about FXR2 antigen include RNA binding; protein binding.
Pathway
RNA transport, organism-specific biosystem; RNA transport, conserved biosystem.

Citations


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References


Kanezaki, R; Toki, T; et al. Cloning and characterization of the novel chimeric gene p53/FXR2 in the acute megakaryoblastic leukemia cell line CMK11-5. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 209:169-180(2006).
Siomi, MC; Zhang, Y; et al. Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. MOLECULAR AND CELLULAR BIOLOGY 16:3825-3832(1996).

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