Anti-FUS monoclonal antibody (DCABH-1673) Knockout Validated

Rabbit anti-Human FUS monoclonal antibody for WB, IHC-P, FC, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS6923
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to a sequence within Human TLS/FUS.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100; Flow Cyt: 1/10 - 1/100; ICC/IF: 1/50 - 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FUS; fused in sarcoma; ALS6, amyotrophic lateral sclerosis 6 , fusion (involved in t(12; 16) in malignant liposarcoma) , fusion, derived from t(12; 16) malignant liposarcoma; RNA-binding protein FUS
Entrez Gene ID
UniProt ID

Product Background


Pathway
Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Suzuki, N; Kato, S; et al. FUS/TLS-Immunoreactive Neuronal and Glial Cell Inclusions Increase With Disease Duration in Familial Amyotrophic Lateral Sclerosis With an R521C FUS/TLS Mutation. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 71:779-788(2012).
Gururaja, T; Li, WQ; et al. Use of MEDUSA-based data analysis and capillary HPLC-ion-trap mass spectrometry to examine complex immunoaffinity extracts of RbAp48. JOURNAL OF PROTEOME RESEARCH 1:253-261(2002).

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