FTCD (NP_996848, 440 a.a. ~ 541 a.a) partial recombinant protein with GST tag. The sequence is LQEGLRRAVSVPLTLAETVASLWPALQELARCGNLACRSDLQVAAKALEMGVFGAYFNVL INLRDITDEAFKDQIHHRVSSLLQEAKTQAALVLDCLETRQE
The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]
Pathway
Histidine catabolism; Histidine metabolism; Metabolism of amino acids and derivatives; One carbon pool by folate
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