Fusion protein corresponding to residues near the N terminal of human fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:200-1:1000
General Notes
This product (Catalog No. DPABH-19079) is a rabbit-derived IgG polyclonal antibody raised against human FSCN1. It has been affinity purified by protein A. This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. DPABH-19079 is suitable for use in Western blot (WB) (1:200–1:1,000) application. DPABH-19079 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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