General Notes
This product (Catalog No. DPABH-22967) is a rabbit-derived polyclonal antibody raised against human FGF2, targeting the amino acid region 143–288 of the protein. This antibody exhibits cross-reactivity with Human FGF2 from mouse and rat. It has been affinity purified by Protein A. Fibroblast growth factor 2 (FGF2), also known as basic fibroblast growth factor (bFGF), is a multifunctional signaling protein encoded by the FGF2 gene located on human chromosome 4q27–28. Belonging to the fibroblast growth factor family, FGF2 exists in multiple isoforms generated through alternative translation initiation from a single mRNA, including the low-molecular-weight 18 kDa form and high-molecular-weight variants (22–34 kDa), which differ in their N-terminal extensions and subcellular localization. It acts primarily as a paracrine and intracrine factor, binding to fibroblast growth factor receptors (FGFRs 1–4) in complex with heparan sulfate proteoglycans to regulate essential cellular processes such as proliferation, differentiation, migration, and survival across diverse tissues.
DPABH-22967 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-22967 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
Publication 
Loading ......
