Specifications
Immunogen
A synthetic peptide of human FBXO17 is used for rabbit immunization.
Target
Alternative Names
FBXO17; F-box protein 17; F box only protein 17 , FBXO26; F-box only protein 17; F box only protein 26; FBG4; Fbx17; FLJ11798; FLJ25205; MGC9379; F-box protein FBG4; F-box only protein 26; FBX26; FBXO26; FLJ58300;
Product Background
Antigen Description
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing of this gene results in 2 transcript variants encoding different isoforms.
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Selenium Metabolism and Selenoproteins, organism-specific biosystem.
Citations
Publication ()
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