Synthetic peptide within Human FAM155B aa 11-60 (N terminal). The exact sequence is proprietary. Isoform 2 (NP_056501.2).Sequence: KDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADH Database link: O75949-2
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
FAM155B; family with sequence similarity 155, member B; TED; TMEM28; CXorf63; bB57D9.1; transmembrane protein FAM155B; bB57D9.1 (TED protein); transmembrane protein 28;
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Citations
Publication ()
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