Anti-FADD monoclonal antibody (DCABH-903)

Mouse anti-Human FADD monoclonal antibody for WB, FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2D22
Species Reactivity
Human
Immunogen
Recombinant full length Human FADD produced in HEK293T cells (NP_003815).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; Flow Cyt: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FADD; Fas (TNFRSF6)-associated via death domain; protein FADD; Fas associating death domain containing protein; Fas associating protein with death domain; GIG3
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of Pro-Caspase 8, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem;

Citations


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References


Seino, K; Setoguchi, Y; et al. Protection against Fas-mediated and tumor necrosis factor receptor 1-mediated liver injury by blockade of FADD without loss of nuclear factor-kappa B activation. ANNALS OF SURGERY 234:681-688(2001).
Swindall, AF; Bellis, SL; et al. Sialylation of the Fas Death Receptor by ST6Gal-I Provides Protection against Fas-mediated Apoptosis in Colon Carcinoma Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 286:22982-22990(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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