Anti-Coagulation Factor III polyclonal antibody [Biotin]

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CoagulationFactorIII/TissueFactor . Gly34-Glu251 Accession Number P13726

Conjugate

Application Notes

Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4099 - DPABY-538

Alternative Names

F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor;

Entrez Gene ID

UniProt ID

Antigen Description

Coagulation Factor III/Tissue Factor (TF), also known as Thromboplastin and CD142, is an integral membrane protein found in a variety of cell types. It functions as a protein cofactor/receptor of coagulation factor VII, which is synthesized in the liver and circulated in the plasma. Synthesized as a 295 amino acid precursor, TF consists of a signal peptide (residues 1 to 32) and the mature chain (residues 33 to 295), which includes a transmembrane region (residues 252 to 274) and a cytoplasmic tail (residues 275 to 295).

Pathway

Complement and Coagulation Cascades; Complement and coagulation cascades; Extrinsic Pathway; Formation of Fibrin Clot (Clotting Cascade); Hemostasis;