Anti-EZR monoclonal antibody, clone 4D23

Name: Anti-EZR monoclonal antibody, clone 4D23
SKU: DCABH-8812
Rating: 5 (1 reviews)

Mouse anti-Human EZR monoclonal antibody for IHC-FoFr, WB, ICC/IF, IHC-P, IHC-Fr, FC

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG1

Clone

4D23

Species Reactivity

Mouse; Rat; Hamster; Cow; Human; Pig; Kangaroo; Monkey

Immunogen

Recombinant fragment, corresponding to amino acids 362-585 of Human Ezrin.

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/100 - 1/750; IHC-P: 1/50 - 1/100; IHC-Fr: 1/50 - 1/100; Flow Cyt: 1μg/10⁶ cells.

Target

Alternative Names

EZR; ezrin; VIL2, villin 2 (ezrin); cytovillin 2; p81; villin-2; villin 2 (ezrin); CVL; CVIL; VIL2; MGC1584; FLJ26216; DKFZp762H157;

Entrez Gene ID

7430

UniProt ID

P15311

Product Background

Antigen Description

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Pathway

Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; FAS (CD95) signaling pathway, organism-specific biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem; L1CAM interactions, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem;

Citations