Specifications
Immunogen
EXOC3 (NP_009208, 646 a.a. - 746 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications
Application Notes
WB: 1:500-1000
Target
Alternative Names
EXOC3; exocyst complex component 3; SEC6 like 1 (S. cerevisiae) , SEC6L1; Sec6p; SEC6-like 1; Sec 6 homolog; exocyst complex component Sec6; SEC6; SEC6L1;
Product Background
Antigen Description
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Pathway
Arf6 trafficking events, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Synthesis and Processing, organism-specific biosystem; Stabilization and expansion of the E-cadherin adherens junction, organism-specific biosystem; Tight junction, organism-specific biosystem.
Citations
Publication ()
Have you cited CAB-3275MH in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
