Anti-EXO1 polyclonal antibody (DPABH-23368)

Rabbit Anti-Human EXO1 (aa 50-150) polyclonal antibody for ICC/IF, WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human Exonuclease 1.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 5 μg/ml; WB: 1/250.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EXO1; exonuclease 1; HEX1; hExoI; hExo1; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Mismatch repair; Mismatch repair;

Citations


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References


Eccleston, J; Schrader, CE; et al. Class Switch Recombination Efficiency and Junction Microhomology Patterns in Msh2-, Mlh1-, and Exo1-Deficient Mice Depend on the Presence of mu Switch Region Tandem Repeats. JOURNAL OF IMMUNOLOGY 183:1222-1228(2009).
Bardwell, PD; Woo, CJ; et al. Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. NATURE IMMUNOLOGY 5:224-229(2004).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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