Anti-ESRP2 (aa 107-322) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant protein fragment, corresponding to a region within amino acids 107-322 of Human ESRP2 (Uniprot ID Q9H6T0)

Conjugate

Application Notes

WB: 1/500 - 1/3000; ICC/IF: 1/100 - 1/1000.

Alternative Names

ESRP2; epithelial splicing regulatory protein 2; RBM35B, RNA binding motif protein 35B; FLJ21918; RNA-binding protein 35B; RNA binding motif protein 35A; RNA binding motif protein 35B; RNA-binding motif protein 35B; RBM35B; FLJ22248;

Entrez Gene ID

UniProt ID

Antigen Description

mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.