Recombinant fragment, corresponding to a region within amino acids 204-406 of Human TXNDC4.
Conjugate
Unconjugated
Target
Alternative Names
ERP44; endoplasmic reticulum protein 44; PDIA10; TXNDC4; endoplasmic reticulum resident protein 44; ER protein 44; thioredoxin domain-containing protein 4; endoplasmic reticulum resident protein 44 kDa; protein disulfide isomerase family A, member 10; thi
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Citations
Publication ()
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