Recombinant full length mature protein, corresponding to amino acids 30-406 of Human TXNDC4 with 26kDa proprietary tag (AAH05374).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000; IHC-P: 3 - 5 μg/ml;
Target
Alternative Names
ERP44; endoplasmic reticulum protein 44; thioredoxin domain containing 4 (endoplasmic reticulum) , TXNDC4; endoplasmic reticulum resident protein 44; KIAA0573; PDIA10; protein disulfide isomerase family A; member 10; ER protein 44; thioredoxin domain-cont
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Citations
Publication ()
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COA
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