Anti-EREG monoclonal antibody (DMABT-H16764)

Mouse anti-Human EREG monoclonal antibody for I-ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
294736
Species Reactivity
Human
Immunogen
Purified Recombinant Human Epiregulin (>98%)
Conjugate
Unconjugated

Target


Alternative Names
EREG; epiregulin; proepiregulin; ER
Entrez Gene ID
UniProt ID

Product Background


Pathway
ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; GRB2 events in ERBB2 signaling, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem;

Citations


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References


Oliveras-Ferraros, C; Vazquez-Martin, A; et al. Interferon/STAT1 and neuregulin signaling pathways are exploratory biomarkers of cetuximab (Erbitux (R)) efficacy in KRAS wild-type squamous carcinomas: A pathway-based analysis of whole human-genome microarray data from cetuximab-adapted tumor cell-line models. INTERNATIONAL JOURNAL OF ONCOLOGY 39:1455-1479(2011).
Strimpakos, A; Pentheroudakis, G; et al. The Prognostic Role of Ephrin A2 and Endothelial Growth Factor Receptor Pathway Mediators in Patients With Advanced Colorectal Cancer Treated With Cetuximab. CLINICAL COLORECTAL CANCER 12:267-274(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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