Anti-EPB41 (aa 116-225) polyclonal antibody

Species Reactivity

Human

Immunogen

EPB41 (AAH39079, 116 a.a. ~ 225 a.a) partial recombinant protein with GST tag. The sequence is IEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEG LEECSKIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECV

Conjugate

Alternative Names

EPB41; erythrocyte membrane protein band 4.1; HE; EL1; 4.1R; protein 4.1; P4.1; EPB4.1; band 4.1; elliptocytosis 1, RH-linked; erythrocyte surface protein band 4.1;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009]

Pathway

Syndecan-2-mediated signaling events;