Specifications
Immunogen
A synthetic peptide of human ENTPD4 is used for rabbit immunization.
Target
Alternative Names
ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4; LYSAL1, lysosomal apyrase like 1; KIAA0392; LALP70; LAP70; NTPDase 4; UDPase; golgi luminal UDPase; uridine-diphosphatase; lysosomal apyrase-like 1; guanosine-diphosphatase like protein; lysosomal
Product Background
Antigen Description
ENTPD4 (Ectonucleoside triphosphate diphosphohydrolase 4) preferentially hydrolyzes nucleoside 5'-diphosphates. Nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP. AMP, ADP, ATP and UMP are not substrates. There are two named isoforms. The preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.
Pathway
Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem.
Citations
Publication ()
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