Synthetic peptide within Human ENAH aa 541-591 (C terminal). The exact sequence is proprietary. NP_001008493.1Sequence: SQPSANGVQT EGLDYDRLKQ DILDEMRKEL TKLKEELIDA IRQELSKSNT A Database link: Q8N8S7
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. Required for the actin-based mobility of Listeria monocytogenes.
Pathway
Adaptive Immune System; Axon guidance; CDC42 signaling events; Developmental Biology; E-cadherin signaling in the nascent adherens junction; Generation of second messenger molecules; Immune System
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