Synthetic peptide within Human ENAH aa 541-591 (C terminal). The exact sequence is proprietary. NP_001008493.1Sequence: SQPSANGVQT EGLDYDRLKQ DILDEMRKEL TKLKEELIDA IRQELSKSNT A Database link: Q8N8S7
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. Required for the actin-based mobility of Listeria monocytogenes.
Pathway
Adaptive Immune System; Axon guidance; CDC42 signaling events; Developmental Biology; E-cadherin signaling in the nascent adherens junction; Generation of second messenger molecules; Immune System
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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Merjonen, P; Keltikangas-Jarvinen, L; et al. Hostility in adolescents and adults: a genome-wide association study of the Young Finns. TRANSLATIONAL PSYCHIATRY 1:-(2011).
Goswami, S; Philippar, U; et al. Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo. CLINICAL & EXPERIMENTAL METASTASIS 26:153-159(2009).
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COA
Certificate of Analysis
