This product (Catalog No. DPABH-05329) is a rabbit-derived polyclonal antibody raised against human ELMO1. This antibody exhibits cross-reactivity with ELMO1 from mouse. It has been affinity purified by Protein A. This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. DPABH-05329 is suitable for use in IHC (1:30–1:150) application. DPABH-05329 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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