Anti-eIF4E3 polyclonal antibody (DPABH-22470)

Rabbit anti-Human eIF4E3 (aa 175-224) polyclonal antibody for WB Datasheet

Online Inquiry Add to basket

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to a region within C terminal amino acids 175-224 (VQVWNVNASL VGEATVLEKI YELLPHITFK AVFYKPHEEH HAFEGGRGKH) of Human EIF4E3 (NP_001128123).
Conjugate
Unconjugated

Applications


Application Notes
WB: 0.5 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EIF4E3; eukaryotic translation initiation factor 4E family member 3; eIF-4E3; eIF4E-3; eukaryotic translation initiation factor 4E type 3
Entrez Gene ID
UniProt ID

Product Background


Gene summary
EIF4E3 (Eukaryotic Translation Initiation Factor 4E Family Member 3) is a Protein Coding gene. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include RNA binding and translation initiation factor activity. An important paralog of this gene is EIF4E1B. EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al. , 2004 [PubMed 15153109]).
Antigen Description
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity. May act as an inhibitor of EIF4E1 activity (By similarity). Eukaryotic translation initiation factor 4E family member 3 is a protein that in humans is encoded by the EIF4E3 gene. 0The function about eIF4E3 antigen include translation initiation factor activity.
Pathway
Antiviral mechanism by IFN-stimulated genes; ISG15 antiviral mechanism; Interferon Signaling.

Citations


Have you cited DPABH-22470 in a publication? Let us know and earn a reward for your research.

References


Cui, J; Han, SY; et al. c-Jun NH2-terminal kinase 2 alpha 2 promotes the tumorigenicity of human glioblastoma cells. CANCER RESEARCH 66:10024-10031(2006).

Related Products


Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-eIF4E3 polyclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket