EEF1A2 (NP_001949, 364 a.a. ~ 462 a.a) partial recombinant protein with GST tag. The sequence is HTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGR FAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAG
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer.
Pathway
Eukaryotic Translation Elongation; Legionellosis; Metabolism of proteins; RNA transport
Citations
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