Anti-EDNRB polyclonal antibody (DPABH-27428)

Rabbit anti-Mouse EDNRB (aa 424-442) polyclonal antibody for WB, IHC-P, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide: KANDHGYDNFRSSNKYSSS conjugated to KLH, corresponding to C terminal amino acids 424-442 of Mouse Endothelin B Receptor.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/5000; IHC-P: 1/2000; ICC/IF: 1/5000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EDNRB; endothelin receptor type B; ETb; ET-B; ET-BR; ETR-b
Entrez Gene ID
UniProt ID

Product Background


Pathway
Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling; GPCRs, Class A Rhodopsin-like

Citations


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References


Loupe, J; Sampath, S; et al. Familial co-segregation of Coffine-Lowry syndrome inherited from the mother and autosomal dominant Waardenburg type IV syndrome due to deletion of EDNRB inherited from the father. EUROPEAN JOURNAL OF MEDICAL GENETICS 57:562-566(2014).
Gunadi; Kapoor, A; et al. Effects of RET and NRG1 polymorphisms in Indonesian patients with Hirschsprung disease. JOURNAL OF PEDIATRIC SURGERY 49:1614-1618(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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