Anti-E1A monoclonal antibody (DMABT-H21000)

Mouse anti-E1A monoclonal antibody for IP, WB, ICC Datasheet

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Host Species
Antibody Isotype
Species Reactivity
trpE-Ad2 E1A fusion protein isolated from E. coli


Alternative Names
Control protein E1A antibody; E1A antibody; Mouse Anti-E1A Monoclonal Antibody; Anti-E1A Monoclonal Antibody; E1A Monoclonal Antibody Mouse Anti-E1A MAb; Anti-E1A MAb

Product Background

Antigen Description
The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.


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Qi, YX; Guo, HH; et al. Preclinical pharmacology and toxicology study of Ad-hTERT-E1a-Apoptin, a novel dual cancer-specific oncolytic adenovirus. TOXICOLOGY AND APPLIED PHARMACOLOGY 280:362-369(2014).
Pospelov, VA; Pospelova, TV; et al. Characterization of the SRF DNA-binding activity in cells transformed with oncogene Ha-ras. MOLECULAR BIOLOGY 30:527-532(1996).

Custom Antibody Labeling

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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