Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
Pathway
Deadenylation-dependent mRNA decay; Decapping complex; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1); Destabilization of mRNA by Tristetraprolin (TTP); Gene Expression; RNA degradation;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-23366 in a publication? Let us know and earn a reward for your research.
Yang, WH; Bloch, DB; et al. Probing the mRNA processing body using protein macroarrays and "autoantigenomics". RNA-A PUBLICATION OF THE RNA SOCIETY 13:704-712(2007).
Yang, WH; Yu, JH; et al. RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules. RNA-A PUBLICATION OF THE RNA SOCIETY 12:547-554(2006).
Payment methods we support:
Invoice / Purchase Order
Credit card
My Review for Anti-DCP1A polyclonal antibody
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Certificate of Analysis
