DCP1A (NP_060873, 186 a.a. ~ 285 a.a) partial recombinant protein with GST tag. The sequence is STQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERL PGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQ
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants.
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