Anti-DYNC1H1 (aa 733-832) polyclonal antibody

Species Reactivity

Human

Immunogen

DNCH1 (AAH21297, 733 a.a. ~ 832 a.a) partial recombinant protein with GST tag. The sequence is TSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVT LPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE

Conjugate

Alternative Names

DYNC1H1; dynein, cytoplasmic 1, heavy chain 1; p22; DHC1; DNCL; DYHC; HL-3; DHC1a; DNCH1; DNECL; Dnchc1; SMALED1; cytoplasmic dynein 1 heavy chain 1; dynein heavy chain, cytosolic; dynein, cytoplasmic, heavy polypeptide 1;

Entrez Gene ID

UniProt ID

Antigen Description

Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family.

Pathway

Adaptive Immune System; Cell Cycle, Mitotic; G2/M Transition; Lissencephaly gene (LIS1) in neuronal migration and development