Anti-DYNC1H1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human DYNC1H1 is used for rabbit immunization.

Conjugate

Alternative Names

DYNC1H1; dynein, cytoplasmic 1, heavy chain 1; DNCH1, DNCL, DNECL, dynein, cytoplasmic, heavy polypeptide 1; cytoplasmic dynein 1 heavy chain 1; DHC1; Dnchc1; HL 3; p22; dynein heavy chain, cytosolic; cytoplasmic dynein heavy chain 1; dynein, cytoplasmic,

Entrez Gene ID

UniProt ID

Antigen Description

Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family.

Pathway

Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Lissencephaly gene (LIS1) in neuronal migration and development, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization??from the centrosome, organism-specific biosystem;