Rabbit Anti-Human DUSP10 (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Fusion protein corresponding to residues near the C terminal of human dual specificity phosphatase 10

Conjugate

Application Notes

WB: 1:200-1:1000
IHC: 1:25-1:100

General Notes

This product (Catalog No. DPABH-14215) is a rabbit-derived IgG polyclonal antibody raised against human DUSP10. This antibody exhibits cross-reactivity with DUSP10 from mouse. It has been affinity purified by protein A. Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.
DPABH-14215 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:25–1:100) applications.
DPABH-14215 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

MKP5; MKP-5

Entrez Gene ID

UniProt ID