DUS2L; dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae); dihydrouridine synthase 2 like (SMM1, S. cerevisiae); tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; DUS2; FLJ20399; SMM1; hDUS2; up-regulated in lung cancer 8; up-regulated in lung ca
DUS2L is a dihydrouridine synthase that catalyzes the reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA.
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