Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide corresponding to residues near the C terminus of Human CRMP2 (UniProt ID: Q16555).
Applications
Application Notes
WB: 1/10000 - 1/50000; IP: 1/10 - 1/100; IHC-P: 1/100 - 1/250; Flow Cyt: 1/10 - 1/1000; ICC/IF: 1/50 - 1/100;
Target
Alternative Names
DPYSL2; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; CRMP2; DHPRP2; DRP 2; DRP2; unc-33-like phosphoprotein 2; collapsin response mediator protein hCRMP-2; N2A3; DRP-2; ULIP2; CRMP-2; ULIP-2;
Product Background
Antigen Description
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Pathway
Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; CRMPs in Sema3A signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Recycling pathway of L1, organism-specific biosystem;
Citations
Publication ()
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