Anti-DOK6 monoclonal antibody (DCABH-11315) Made to order

Rabbit anti-Human DOK6 monoclonal antibody for WB, ELISA

View other DOK6 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human DOK6 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
DOK6; docking protein 6; docking protein 5 like , DOK5L; HsT3226; MGC20785; downstream of tyrosine kinase 6
Entrez Gene ID
UniProt ID

Product Background


Gene summary
DOK6 (Docking Protein 6) is a Protein Coding gene. Among its related pathways are Signaling events regulated by Ret tyrosine kinase. GO annotations related to this gene include insulin receptor binding. An important paralog of this gene is DOK1. DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al. , 2004 [PubMed 15286081]).
Antigen Description
DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al. , 2004 [PubMed 15286081]). DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. The function about DOK6 antigen include insulin receptor binding.
Pathway
Signaling events regulated by Ret tyrosine kinase, organism-specific biosystem.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Qian, JN; El Khoury, G; et al. A synthetic Protein G adsorbent based on the multi-component Ugi reaction for the purification of mammalian immunoglobulins. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 898:15-23(2012).
Chen, R; Weng, ZP; et al. A novel shape complementarity scoring function for protein-protein docking. PROTEINS-STRUCTURE FUNCTION AND GENETICS 51:397-408(2003).

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